1. Concept of SCIHB
The concept essence consists in the following. It is possible to present
biomolecules and biostructures
in the form of two types of elementary combinations from organogenic
elements (C, N, O, P, S). The first type of combinations
is simple groups RZ, which consist of two
atoms of the organogenic elements linked with a s-bond. The second type of combinations - resonance groups
- Q-R=X - consist of three organogenic elements
linked with two s-bonds and one p-bond, which capable migrate (displace) (QR=X ßà Q=RX) like in
resonance structures considered by L. Pauling. In the book the table of such
combinations including 5 simple and 15 resonance groups have been suggested,
which are classified according to their molecular masses.
Classification of groups encountered in biomolecules
and biostructures
|
Simple groups (RZ) |
Resonance groups (QR=X) |
||
|
CC CN CO CS |
CC=C CC=N CC=O CC=S |
NC=N NC=O NC=S |
OC=O OC=S |
|
- |
CP=O |
NP=O |
OP=O |
|
SS |
CS=O |
NS=O |
OS=O |
Not stopping on details, we will
notice, that on the basis of the analysis of interaction of these groups among
themselves through atom of hydrogen, in the book it is shown, that the most groups
can interact with each other through a hydrogen atom thus generating two types
of systems:
a)
Systems
of resonance groups:
HQ1R=X1...HQ2R=X2...HQ3R=X3... ...HQnR=Xn...
b) Systems of alternating resonance and simple groups:
R
R
|
|
HQ1R=X1...HZ1...HQ2R=X2...HQ3R=X3... ...HQnR=Xn...HZm
Owing to similarity of such systems to the polyconjugated systems and presence in them of atoms of
hydrogen, such systems are named in the book by "Systems of the Conjugated
Ionic-Hydrogen Bonds, in abbreviated form SCIHB. From here
and the concept name - concept of SCIHB.
They are not something new and absolutely unknown in biology, but thanks to a
description generality, get new quality - universality. As the book affirms,
that similar systems are a construction basis of supramolecular
biological structures and charge (and energy) transfer channels in these
structures. This statement is supported by the analysis of a considerable
quantity of the modern experimental data received mainly on the basis of
studying of concrete biostructures (proteins and their
complexes with other structures).
Transition to Section 2: Charge transfer model in SCIHB